The research

Regeneration :
the new anti-aging

C27 products are not just cosmetics. These are real alchemies which naturally help to regenerate the skin and maintain its vital balance [homeostasis], its beauty and ultimately its longevity.

The skin is one of the organs that most visibly reflects the skin aging process aggravated and accelerated by our lifestyles, habits, stress level and environmental conditions. To maintain our skin, we must stimulate the regeneration of our proteins and protect it from excessive oxidation.

Aging is a natural and inevitable physiological process, but we have found a way to slow it down by reducing the oxidation of the proteome (skin proteins).

Skin regeneration is the new anti-aging and the basis of skin longevity, from the age of 27. All our products contain Centella Asiatica extracts, the skin's "secret to longevity", in different forms and concentrations.

Formulas
Green-Tech and Biomimetics

Uncompromising formulas which are scholarly compositions, all designed by Michèle EVRARD.

C27 formulas are the subject of precise and expert formulatory know-how that is constantly being improved, which consists of reproducing the structure of the skin in order to provide better penetration of the product. These are biomimetic formulas, that is to say they blend into the biological functioning of the skin allowing better bioavailability of active ingredients and therefore potentiating the effects of the formula on the skin.

C27's "green-tech" philosophy combines the latest formulation technologies with clean, conscious ingredient excellence, biotechnology and green chemistry. Each of our formulas combines the uncompromising choice of active and non-active ingredients.

Centella Asiatica
a prodigious plant

Centella Asiatica is an ancient medicinal plant used in Ayurvedic and other South Asian medicines. It is recognized for its regenerative properties and as the “plant of longevity”.

The plant used in C27 formulas comes exclusively from Madagascar because it has a higher concentration of purified active ingredients (heterosides).

In addition, it is cultivated manually according to the climate and the seasons. The Centella “economy” contributes to the income of local populations (eco-commerce). A sustainable source, in line with the company's values.

The CICA-MA2® Complex: proprietary ingredient C27

This patented C27 ingredient is an exclusive, clinically proven complex that concentrates the very essence of the most active purified extracts of the plant, [Asiaticoside, Madecassoside and Asian acid]

They have been combined in higher ratios and concentrations and are not naturally present in the plant. Different concentration levels were tested before defining the exact and perfect ratios which revealed the regenerative and restorative power of the complex.

The CICA-MA2® complex was subjected to a battery of tests carried out on skin aging with a laboratory specializing in proteome research. Ex-vivos tests made it possible to demonstrate the extraordinary positive effect of the CICA-MA2® complex on this process with, on the one hand, the slowing down of carboxylation (oxidation) of the proteome. The skin proteome corresponds to all skin proteins such as collagens, keratins and laminins. These are called biomarkers of aging.

On the other hand, the regeneration of these biomarkers of skin aging. Among these biomarkers of aging that we have studied, the most revealing of the activity of the complex are
Collagen XVII and Keratin 14.

Collagen XVII : A fundamental protein of the skin. It controls and regulates the proliferation of cells in the epidermis by intervening in the competition between skin stem cells. Thus they are considered to be the longevity protein of the skin.

Keratin 14 : It plays a fundamental role in regulating the renewal of the epidermis. This mechanism allows us to maintain an effective skin barrier, therefore promoting skin longevity.